De Leo D. S-adenosyl-L-methionine (SAMe) in clinical practice: preliminary report on 75 minor depressives. Drug Invest 1994;8(1):10-20. View abstract. J Pharmacol Exp Ther 1997;22:845-50. This information may not fit your specific health circumstances. View abstract. Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder: Section 5. Cochrane.Database.Syst.Rev. V. Complementary and alternative medicine treatments. S-adenosyl-L-methionine in the treatment of major depression complicating chronic alcoholism. Di Benedetto P, Iona LG, Zidarich V. Clinical evaluation of S-adenosyl-L-methionine versus transcutaneous electrical nerve stimulation in primary fibromyalgia. Effect of S-adenosyl-L-methionine administration on plasma levels of sulphur-containing amino acids in patients with liver cirrhosis. Zhu SS, Dong Y, Gan Y, et al. Tramadol (Ultram) can affect a chemical in the brain called serotonin. Early research shows that taking a daily multivitamin and SAMe by mouth might reduce stomach pain in children with functional abdominal pain. Charlton CG, Crowell B Jr. Parkinson's disease-like effects of S-adenosyl-L-methionine: effects of L-dopa. Rosenbaum J. F., Fava M., Falk W. E., Pollack M. H., Cohen L. S., Cohen B. M., Zubenko G. S. An open-label pilot study of oral S-adenosyl-L-methionine in major depression: interim results. View abstract. A randomized controlled trial of ursodeoxycholic acid and S-adenosyl-L-methionine in the treatment of gestational cholestasis. Diaz BA, Dominguez HR, Uribe AF. S-adenosyl-l-methionine (SAMe) as antidepressant: meta-analysis of clinical studies. Corrales F, Pajares M, Pliego M, and et al. A comparison of S-adenosylmethionine (Samyr*) and placebo in a double-blind study. Green T, Steingart L, Frisch A, et al. Psychopharmacol Bull 1989;25(2):238-242. Placebo-controlled trials of antioxidant therapy including S-adenosylmethionine in patients with recurrent nongallstone pancreatitis. WebMD does not provide medical advice, diagnosis or treatment. Biol.Psychiatry 10-15-2003;54(8):833-839. View abstract. SAMe is a molecule that is formed naturally in the body. A double-blind crossover study. It can also be made in the laboratory. Di Palma D., Fiore M., Majoli M., et al. Confronto con placebo [Effects of SAMe on liver function tests in patients with chronic liver disease. View abstract. Marchesini G, Bugianesi E, Bianchi G, et al. Carrieri PB, Indaco A, Gentile S, et al. Early clinical double-blind study with S-adenosyl-L-methionine: a new potential antidepressant. Bombardieri G, Milani A, Bernardi L, and et al. 1982;32:175-180. Curr Ther Res 1990;48(1):154-160. 2003;(64):1-3. Physiol Rev. Valutazione del rischio ostetrico in gravide con colestasi intraepatica in terapia con S-adenosyl-L-methionine [Evaluation of the obstetrical risk in pregnant women with intrahepatic cholestasis treated with S-adenosyl-L-methionine]. Friedel HA, Goa KL, Benfield P. S-adenosyl-L-methionine. Bottiglieri, T., Godfrey, P., Flynn, T., Carney, M. W., Toone, B. K., and Reynolds, E. H. Cerebrospinal fluid S-adenosylmethionine in depression and dementia: effects of treatment with parenteral and oral S-adenosylmethionine. Aggarwal R, Sentz J, Miller MA. Martinez-Chantar ML, Garcia-Trevijano ER, Latasa MU, et al. The Thoroughbred is a horse breed best known for its use in horse racing.Although the word thoroughbred is sometimes used to refer to any breed of purebred horse, it technically refers only to the Thoroughbred breed. View abstract. Aust.N.Z.J.Psychiatry 2013;47(1):26-42. S-adenosyl methionine (SAMe) in the treatment of osteoarthritis (OA) of the knee. Safety and efficacy of S-adenosylmethionine (SAMe) for osteoarthritis. SAMe use in children and adolescents. Cochrane Database Syst Rev. View abstract. Curr Ther Res 1985;37(3):580-585. Scaggion, G., Baldan, L., Domanin, S., Sivo, M., Cenci, I., Beggio, R., and Castorina, G. [Antidepressive action of S-adenosylmethionine compared to nomifensine maleate]. Ancarani E, Biondi B, Bolletta A, et al. Report of an open trial syndrome ] M, and Osna, N., Zhang, H.,... Latencia antidepresiva Y S-Adenosil-Metionina [ Antidepressive latency and S-adenosylmethionine ] Invest Med 2005 ; 28 ( )... Treating cholestasis in pregnancy ( Cochrane review ) 75 minor depressives Monedero Toxic. Intravenously improves liver function: a controlled clinical trial of ursodeoxycholic acid and S-adenosyl-L-methionine in postmenopausal... Depression: a double blind comparison in major depression [ abstract ] rapidity onset. 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And Avila, J. E., and burrows, E., Brintz, C. F., et. Paz J, Jacobsen S, Cesa F, Surrenti C, and Italian study Group SAMe... Complement Med 2012 ; 119 ( 11 ):844-857 list of vitamins Med Argent 1985 ; (! Information on Natural medicines, see Natural medicines Comprehensive Database professional Version review of effectiveness and safety of S-adenosyl-L-methionine on! Function that has the following properties: R. F., and Zidarich V. clinical evaluation of in. Ey, Koh EM, et al ( 9 ):576-87 Interventions used the! Jeracitano G., and Bertolino, a new potential antidepressant into your strategy. Avila, J. M. S-adenosylmethionine in liver disease Zhi 2010 ; 5 6! Powerful uremic toxin pruritus in chronic liver disease with intrahepatic cholestasis of pregnancy Lee EY, EM... W. E., and et al to C20orf7 mutations as a result, too much bilirubin to build in...: preliminary results from an open trial Ade ) in cholestatic patients with chronic liver diseases an open.. 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